The stakes may hardly be greater for the Democratic vice chairman and Republican former president, with tens of thousands and thousands of American voters anticipated to tune in at 9.00pm Japanese Time (0100 GMT Wednesday) to look at their first and presumably solely debate.
A single zinger or gaffe may tip the stability of one of the dramatic White Home races in US historical past, with the 2 rivals neck-and-neck within the polls forward of the November 5 vote.
For Harris, 59, will probably be a vital probability to win over voters who nonetheless know little about her, as her honeymoon starts to fade after suddenly replacing President Joe Biden in July.
Trump, 78, will in the meantime attempt to field in Harris on points just like the financial system and immigration, however may additionally unleash extra of the racist and sexist insults that he is directed her manner in the course of the marketing campaign.
Harris, who enjoys a big benefit amongst girls in accordance with the polls, is predicted to press Trump on reproductive rights after he made a variety of seemingly contradictory feedback lately on abortion entry.